[Science] How Fucoidan help diabetics to fight COVID-19 and reduce the risk of severe illness?
How Fucoidan help diabetics to fight COVID-19 and reduce the risk of severe illness?
Experiments have confirmed that fucoidan can improve the damage and dysfunction of pancreatic β-cells in diabetic mice. The main mechanism is to reduce the death of pancreatic β-cells, and regulate PDX-1 and GLP1-R via the Sirt-1-dependent pathway to increase insulin synthesis. Therefore, foods or supplements containing fucoidan may be able to control diabetes by preventing the damage of pancreatic β cells.
Diabetes and COVID-19 infection interact with each other and develop in a vicious circle, significantly increasing the rate of severe illness and mortality, bringing great difficulties to the control of the epidemic, and posing a major threat to patients and their families. Diabetes patients need to be more active in their own protection and strengthen blood sugar management and control to reduce the risk of severe illness!
- XuanX, GaoF, MaX, et al. Activation of ACE2/angiotensin (1-7) attenuates pancreatic β cell dedifferentiation in a high-fat-diet mouse model. Metabolism, 2018, 81: 83-96
- Mol. Nutr. Food Res. 61, 10, 2017, 1700136 DOI 10.1002/mnfr.201700136