Do Heart Disease and Kidney Disease in Pets Affect Each Other?


Are dogs and cats with heart disease also more likely to develop kidney disease?
When pets suffer from both conditions at the same time, does it leave pet parents feeling overwhelmed and at a loss?

Put your worries aside and let the professional guide you. Dr. Chun-Ta Chen explains the cause-and-effect relationship between the heart and the kidneys, and how to care for pets suffering from both conditions, so pet parents can feel more confident and less stressed when caring for their sick fur babies.


Do the heart and kidneys really affect each other’s health?

Whether in humans or animals, the heart and kidneys have a long-standing, interconnected relationship. This is known as cardiorenal syndrome or renocardiac syndrome. Here’s how they influence each other:


️ Cardiorenal Syndrome:

When the heart develops cardiomyopathy or valvular disease, its pumping ability decreases. This reduces blood flow (perfusion) to the kidneys, leading to diminished toxin filtration, elevated kidney values, ischemia, and hypoxia. Over time, kidney cells may undergo irreversible necrosis and fibrosis, forcing the remaining healthy kidney cells to work harder and increasing the overall burden on the kidneys.


️ Renocardiac Syndrome:

This condition is mainly caused by kidney aging combined with factors such as heart disease or hypertension. Poor kidney perfusion stimulates the kidneys and activates the renin–angiotensin–aldosterone system (RAAS), resulting in increased heart rate, fluid retention, vasoconstriction, and elevated blood pressure. Over time, this places additional strain on the heart and leads to progressive deterioration.


How do veterinarians treat pets with both kidney and heart disease?

Veterinarians will first evaluate which condition—heart or kidney disease—is more severe, then choose the most appropriate treatment plan for the pet.

To manage cardiorenal and renocardiac syndromes, doctors aim to improve cardiac output, enhance renal perfusion, and avoid excessive use of diuretics. This helps prevent potassium loss caused by overuse of diuretics and reduces the burden on the kidneys

For kidney management, urine tests are performed. If proteinuria is detected, treatment will be initiated, as improving proteinuria can extend the survival time of pets with kidney disease. Blood pressure control is also crucial for maintaining proper kidney perfusion.

In addition, controlling blood phosphate levels is essential. Chronic kidney disease often leads to hyperphosphatemia, which can cause mucosal damage and calcium–phosphorus imbalance.


How should pet parents manage home care for pets with both heart and kidney disease?

Using cats as an example: after a diagnosis of cardiomyopathy, veterinarians will prescribe medications or provide recommendations based on the stage of the disease.

In addition to prescribed medications, daily supplementation with heart-supportive nutrients is recommended, such as Fucobalan® (low-molecular-weight fucoidan + highly stable fucoxanthin), fish oil, Coenzyme Q10, taurine, and more.

For cats with kidney disease, aside from prescription renal diets, potassium supplementation may be needed to prevent hypokalemia. Phosphate levels should also be controlled. Supplements that promote circulation—such as lanthanum carbonate, fish oil, or kidney-specific amino acids—are also recommended. Regular monitoring of blood pressure and proteinuria is essential, and dietary protein intake should be carefully limited.


Gentle Reminder:

Whether your pet has heart disease, kidney disease, or both, always consult a veterinarian first. A thorough evaluation of each organ’s severity is essential to create the most appropriate treatment and health management plan for your beloved pet.

Reference: https://www.hiq-pets.com/article/97