2025 / 12 / 30

OliFuco® RE: Innovation for Muscle Health and Healthy Aging

As the global population ages, sarcopenia, an age-related condition marked by progressive muscle loss, reduced strength, and functional decline, has emerged as a major health challenge among older adults. Sarcopenia is closely associated with increased risks of falls, frailty, and loss of independence, yet there is currently no approved pharmaceutical treatment.

OliFuco® RE is a proprietary low molecular weight oligo fucoidan developed by Hi-Q Marine Biotech, designed as a marine-based nutritional solution to support muscle health, anti-aging, and inflammation management.


Advanced Oligo Fucoidan Technology by Hi-Q Marine Biotech

Derived from brown seaweed, OliFuco® RE is produced using Hi-Q Marine Biotech’s advanced enzymatic hydrolysis technology, resulting in an ultra-low molecular weight (<1500 Da) fucoidan. This optimized structure allows for improved absorption, higher bioavailability, and preserved bioactivity, overcoming the limitations of traditional high molecular weight fucoidan.


Scientifically Supported Benefits for Sarcopenia

Preclinical studies using accelerated aging mouse models (SAMP8) and muscle cell experiments show that OliFuco® RE supports muscle health through dual mechanisms:

  • Enhancing muscle protein synthesis via activation of the Akt/mTOR signaling pathway, while suppressing muscle atrophy-related genes such as MuRF1
  • Reducing chronic inflammation by lowering key inflammatory markers, including IL-6, TNF-α, and myostatin, which are closely linked to age-related muscle degeneration

These effects contribute to the maintenance of muscle mass, muscle strength, and functional performance in aging populations.


Conclusion

Developed by Hi-Q Marine Biotech, OliFuco® RE represents a next-generation marine-derived functional ingredient targeting sarcopenia, muscle loss, and healthy aging. By addressing both inflammation and muscle protein metabolism, it offers a science-based nutritional approach to preserving mobility and quality of life in later years.


Disclaimer:
This content is based on laboratory and animal studies. Human clinical trials are required to further validate efficacy and optimal dosage. Please consult healthcare professionals before use

Reference: https://www.sciencedirect.com/science/article/pii/S0531556525002839?via%3Dihub