Invitation: Malaysia Technology Expo (MTE)
The Malaysia Technology Expo (MTE) is the largest event in region featuring an expo on innovations, an awards programme honoring innovators in technology that brings transformation to industries, public service, and contributes to sustainability. In 2022, MTE remains to be a virtual event. Hi-Q feels very much honored to be able to take part in this event!
Step1: Register at https://mte.ibentos.com/
Step2: Login and visit the virtual exhibition
Step3: Select [International Innovation Award Room]
Step4: Find [Chinese Innovation and Invention Society] booth
Step5: Find Hi-Q’s Innovation in the booth
Hi-Q’s Innovation (with patents):
Oligo Fucoidan, an Active Substance for Preventing Radiation-Induced Pneumonitis and Lung Fibrosis during Radiotherapy
Radiotherapy (RT) is a crucial treatment approach for many types of cancer, including lung cancer, breast cancer. Since most of the radiation is focused on the chest cavity region, it is easy to cause the common side effects, radiation pneumonitis and fibrosis. Late-stage pulmonary fibrosis can cause long-term coughing, wheezing, chest pain, and even inexplicable fever, affecting the patient's quality of life. Studies have indicated that preventing or treating RT-induced lung injury is difficult. Patients who require chest RT have a risk of this injure, which exerts acute or long-term effects. Therefore, it is necessary to identify an effective prophylactic agent.
In our study, Oligo Fucoidan changes the expression patterns of inflammatory cytokines, which may consequently attenuate radiation pneumonitis and lung fibrosis. Decreased neutrophil and macrophage accumulation was observed in irradiated lung tissues. Oligo Fucoidan administration also changed the expression patterns of inflammatory cytokines in irradiated lung tissues. Furthermore, Oligo Fucoidan significantly reduced the expression levels of TIMP-1, CXCL1, MCP-1, MIP-2, and interleukin-1Ra in the pleural fluid. In conclusion, Oligo Fucoidan can be a potential therapeutic agent for radiation‐induced pneumonitis and lung fibrosis attenuation or prevention.
